c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder

Pablo S. Contreras; Pablo J. Tapia; Lila González-Hódar; Ivana Peluso; Chiara Soldati; Gennaro Napolitano; Maria Matarese; Macarena Las Heras; Cristian Valls; Alexis Martinez; Elisa Balboa; Juan Castro; Nancy Leal; Frances M. Platt; Andrzej Sobota; Dominic Winter; Andrés D. Klein; Diego L. Medina; Andrea Ballabio; Alejandra R. Alvarez; Silvana Zanlungo

doi:10.1016/j.isci.2020.101691

c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder

Pablo S. Contreras, Pablo J. Tapia, Lila González-Hódar, Ivana Peluso, Chiara Soldati, Gennaro Napolitano, Maria Matarese, Macarena Las Heras, Cristian Valls, Alexis Martinez, Elisa Balboa, Juan Castro, Nancy Leal, Frances M. Platt, Andrzej Sobota, Dominic Winter, Andrés D. Klein, Diego L. Medina, Andrea Ballabio, Alejandra R. AlvarezSilvana Zanlungo

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

Biological

Original language	English
Article number	101691
Journal	iScience
Volume	23
Issue number	11
DOIs	https://doi.org/10.1016/j.isci.2020.101691
State	Published - 20 Nov 2020
Externally published	Yes

Keywords

Biological Sciences
Cell Biology
Molecular Biology

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10.1016/j.isci.2020.101691

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Contreras, P. S., Tapia, P. J., González-Hódar, L., Peluso, I., Soldati, C., Napolitano, G., Matarese, M., Heras, M. L., Valls, C., Martinez, A., Balboa, E., Castro, J., Leal, N., Platt, F. M., Sobota, A., Winter, D., Klein, A. D., Medina, D. L., Ballabio, A., ... Zanlungo, S. (2020). c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder. iScience, 23(11), Article 101691. https://doi.org/10.1016/j.isci.2020.101691

@article{774f2b6dc47948a5bfe234e107f6d26a,

title = "c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder",

abstract = "Biological",

keywords = "Biological Sciences, Cell Biology, Molecular Biology",

author = "Contreras, {Pablo S.} and Tapia, {Pablo J.} and Lila Gonz{\'a}lez-H{\'o}dar and Ivana Peluso and Chiara Soldati and Gennaro Napolitano and Maria Matarese and Heras, {Macarena Las} and Cristian Valls and Alexis Martinez and Elisa Balboa and Juan Castro and Nancy Leal and Platt, {Frances M.} and Andrzej Sobota and Dominic Winter and Klein, {Andr{\'e}s D.} and Medina, {Diego L.} and Andrea Ballabio and Alvarez, {Alejandra R.} and Silvana Zanlungo",

note = "Publisher Copyright: {\textcopyright} 2020 The Authors",

year = "2020",

month = nov,

day = "20",

doi = "10.1016/j.isci.2020.101691",

language = "Ingl{\'e}s",

volume = "23",

journal = "iScience",

issn = "2589-0042",

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number = "11",

}

Contreras, PS, Tapia, PJ, González-Hódar, L, Peluso, I, Soldati, C, Napolitano, G, Matarese, M, Heras, ML, Valls, C, Martinez, A, Balboa, E, Castro, J, Leal, N, Platt, FM, Sobota, A, Winter, D, Klein, AD, Medina, DL, Ballabio, A, Alvarez, AR & Zanlungo, S 2020, 'c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder', iScience, vol. 23, no. 11, 101691. https://doi.org/10.1016/j.isci.2020.101691

TY - JOUR

T1 - c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder

AU - Contreras, Pablo S.

AU - Tapia, Pablo J.

AU - González-Hódar, Lila

AU - Peluso, Ivana

AU - Soldati, Chiara

AU - Napolitano, Gennaro

AU - Matarese, Maria

AU - Heras, Macarena Las

AU - Valls, Cristian

AU - Martinez, Alexis

AU - Balboa, Elisa

AU - Castro, Juan

AU - Leal, Nancy

AU - Platt, Frances M.

AU - Sobota, Andrzej

AU - Winter, Dominic

AU - Klein, Andrés D.

AU - Medina, Diego L.

AU - Ballabio, Andrea

AU - Alvarez, Alejandra R.

AU - Zanlungo, Silvana

PY - 2020/11/20

Y1 - 2020/11/20

N2 - Biological

AB - Biological

KW - Biological Sciences

KW - Cell Biology

KW - Molecular Biology

UR - http://www.scopus.com/inward/record.url?scp=85094188778&partnerID=8YFLogxK

U2 - 10.1016/j.isci.2020.101691

DO - 10.1016/j.isci.2020.101691

M3 - Artículo

AN - SCOPUS:85094188778

SN - 2589-0042

VL - 23

JO - iScience

JF - iScience

IS - 11

M1 - 101691

ER -

c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder

Abstract

Keywords

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