Combating Prosthetic Infections: Synthesis, Characterization, and Evaluation of Magnesium-Doped Hydroxyapatite Nanofibers with Antibacterial Properties

Epsiba Lorena Marañon Romero, Ricardo Pascual Alanis Gómez, José Rafael Alanis-Gómez, Kevin José Martínez Arellano, Fabiola Hernández-Rosas, Rodrigo Velázquez Castillo

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Hydroxyapatite (HAp) is one of the most important in the family of calcium phosphates since it is an inorganic component of bone and it has been proven to be a biocompatible, osteoconductive, and osteoinductive material. However, it presents low antimicrobial activity making it susceptible to infections. This work aimed first to synthesize and characterize HAp nanofibers doped with Mg nanoparticles with a growth-oriented crystalline structure and second to evaluate their antimicrobial activity. For this, we synthesized HAp nanofibers by microwave-assisted hydrothermal method and carried out the structural characterization using the X-ray powder diffraction method. The morphological, topological, and microstructural characterization was performedwith scanning electron microscopy. Given the results, synthetic Mg-HAp nanofibers exhibited a hexagonal morphology and high purity and crystallinity. In addition, the nanofunctionality show of Mg-HAp exhibits good antimicrobial activity.

Original languageEnglish
Title of host publication46th Mexican Conference on Biomedical Engineering - Proceedings of CNIB 2023 - Volume 2
Subtitle of host publicationBiomechanics, Rehabilitation and Clinical Engineering
EditorsJosé de Jesús Agustín Flores Cuautle, Balam Benítez-Mata, Ricardo Antonio Salido-Ruiz, Hugo A. Vélez-Pérez, Gustavo Adolfo Alonso-Silverio, Guadalupe Dorantes-Méndez, Aldo Rodrigo Mejía-Rodríguez, Esmeralda Zúñiga-Aguilar, Edgar Del Hierro-Gutiérrez
PublisherSpringer Science and Business Media Deutschland GmbH
Pages131-138
Number of pages8
ISBN (Print)9783031469350
DOIs
StatePublished - 1 Jan 2024
Event46th Mexican Conference on Biomedical Engineering, CNIB 2023 - Villahermosa Tabasco, Mexico
Duration: 2 Nov 20234 Nov 2023

Publication series

NameIFMBE Proceedings
Volume97
ISSN (Print)1680-0737
ISSN (Electronic)1433-9277

Conference

Conference46th Mexican Conference on Biomedical Engineering, CNIB 2023
Country/TerritoryMexico
CityVillahermosa Tabasco
Period2/11/234/11/23

Keywords

  • Antimicrobial Activity
  • Hydroxyapatite
  • Nanobiomaterial

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