TY - JOUR
T1 - Congenital toxoplasmosis
T2 - Specific IgG subclasses in mother/newborn pairs
AU - Canedo-Solares, Irma
AU - Galván-Ramírez, María De La Luz
AU - Luna-Pastén, Héctor
AU - Rodríguez Pérez, Laura Rocío
AU - Ortiz-Alegría, Luz Belinda
AU - Rico-Torres, Claudia Patricia
AU - Vela-Amieva, Marcela
AU - Pérez-Andrade, Martha
AU - Figueroa-DamiÁn, Ricardo
AU - Correa, Dolores
PY - 2008/1/1
Y1 - 2008/1/1
N2 - Anti-Toxoplasma gondii antibodies of all IgG subclasses were studied in mother/newborn pairs. IgG1 in the mothers and IgG3 in the newborns were related to offspring clinical problems; IgG2 and IgG3 in the babies were markers of vertical transmission, and IgG4 in mothers or children were associated to clinical problems. IgG subclasses may be markers of congenital infection or clinical outcome.
AB - Anti-Toxoplasma gondii antibodies of all IgG subclasses were studied in mother/newborn pairs. IgG1 in the mothers and IgG3 in the newborns were related to offspring clinical problems; IgG2 and IgG3 in the babies were markers of vertical transmission, and IgG4 in mothers or children were associated to clinical problems. IgG subclasses may be markers of congenital infection or clinical outcome.
KW - Antibodies
KW - congenital toxoplasmosis
KW - fetal response
KW - IgG subclasses
KW - placenta
UR - http://www.scopus.com/inward/record.url?scp=45849091924&partnerID=8YFLogxK
U2 - 10.1097/INF.0b013e31816591df
DO - 10.1097/INF.0b013e31816591df
M3 - Artículo
C2 - 18520342
AN - SCOPUS:45849091924
SN - 0891-3668
VL - 27
SP - 469
EP - 474
JO - Pediatric Infectious Disease Journal
JF - Pediatric Infectious Disease Journal
IS - 5
ER -