TY - GEN
T1 - Microstructure and Mechanical Properties of Hydroxyapatite Nanofibers Synthesized Through the Microwave-Assisted Hydrothermal Method for Biomedical Applications
AU - Martínez-Arellano, Kevin
AU - Hernández Rosas, Fabiola
AU - Alanís-Gómez, José Rafael
N1 - Publisher Copyright:
© 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG.
PY - 2023/1/1
Y1 - 2023/1/1
N2 - Hydroxyapatite (HAp) is the main mineral component of bones and has various applications in the biomedical area. The objective of this work was first to synthesize and characterize hydroxyapatite nanofibers with a crystalline growth orientation and with a Ca/P ratio similar to bone and secondly to elaborate composite materials with HAp nanofibers that possess mechanical properties similar to trabecular human bone. For this, we synthesized HAp nanofibers by microwave-assisted hydrothermal technique and performed the structural characterization by means of the X-ray powder diffraction method. The morphological, topological, and microstructural characterization was performed with scanning electron microscopy and high-resolution electron microscopy. With HAp as a base, 3 types of porous ceramic materials were obtained using the modified gel casting method. Finally, these composite materials were subjected to mechanical compression tests. Given the results, synthetic HAp nanofibers exhibited a hexagonal morphology, a preferential crystal orientation in the [300] direction, and a purity level of [001]. In addition, a Ca/P ratio similar to that of human bone was obtained. In the mechanical tests, the HAp composite materials got maximum compressive stress of 20 MPa, which corresponds to that required by trabecular bone. In conclusion, the composite material obtained has physicochemical, structural, morphological, and mechanical properties similar to those of natural bone tissue, so it is possible to consider the use of this type of material as a bone replacement.
AB - Hydroxyapatite (HAp) is the main mineral component of bones and has various applications in the biomedical area. The objective of this work was first to synthesize and characterize hydroxyapatite nanofibers with a crystalline growth orientation and with a Ca/P ratio similar to bone and secondly to elaborate composite materials with HAp nanofibers that possess mechanical properties similar to trabecular human bone. For this, we synthesized HAp nanofibers by microwave-assisted hydrothermal technique and performed the structural characterization by means of the X-ray powder diffraction method. The morphological, topological, and microstructural characterization was performed with scanning electron microscopy and high-resolution electron microscopy. With HAp as a base, 3 types of porous ceramic materials were obtained using the modified gel casting method. Finally, these composite materials were subjected to mechanical compression tests. Given the results, synthetic HAp nanofibers exhibited a hexagonal morphology, a preferential crystal orientation in the [300] direction, and a purity level of [001]. In addition, a Ca/P ratio similar to that of human bone was obtained. In the mechanical tests, the HAp composite materials got maximum compressive stress of 20 MPa, which corresponds to that required by trabecular bone. In conclusion, the composite material obtained has physicochemical, structural, morphological, and mechanical properties similar to those of natural bone tissue, so it is possible to consider the use of this type of material as a bone replacement.
KW - Biomaterial
KW - Hydroxyapatite
KW - Nanotechnology
UR - http://www.scopus.com/inward/record.url?scp=85142702279&partnerID=8YFLogxK
U2 - 10.1007/978-3-031-18256-3_74
DO - 10.1007/978-3-031-18256-3_74
M3 - Contribución a la conferencia
AN - SCOPUS:85142702279
SN - 9783031182556
T3 - IFMBE Proceedings
SP - 705
EP - 713
BT - 45th Mexican Conference on Biomedical Engineering - Proceedings of CNIB 2022
A2 - Trujillo-Romero, Citlalli Jessica
A2 - Gonzalez-Landaeta, Rafael
A2 - Chapa-González, Christian
A2 - Dorantes-Méndez, Guadalupe
A2 - Flores, Dora-Luz
A2 - Flores Cuautle, J.J.Agustin
A2 - Ortiz-Posadas, Martha R.
A2 - Salido Ruiz, Ricardo A.
A2 - Zuñiga-Aguilar, Esmeralda
PB - Springer Science and Business Media Deutschland GmbH
T2 - 45th Mexican Conference on Biomedical Engineering, CNIB 2022
Y2 - 6 October 2022 through 8 October 2022
ER -