TY - JOUR
T1 - Osteoporosis in patients with systemic lupus erythematosus
AU - García-Carrasco, Mario
AU - Mendoza-Pinto, Claudia
AU - Escárcega, Ricardo O.
AU - Jiménez-Hernández, Mario
AU - Morales, Ivet Etchegaray
AU - Realpozo, Pamela Munguía
AU - Rebollo-Vázquez, Jaime
AU - Soto-Vega, Elena
AU - Delezé, Margarita
AU - Cervera, Ricard
PY - 2009/8/1
Y1 - 2009/8/1
N2 - In recent years the survival of patients with systemic lupus erythematosus has increased markedly. Consequently, longterm complications, such as osteoporosis, are currently of paramount importance. SLE is known to increase the risk of bone fractures, and numerous studies have found that SLE patients have osteoporosis. Of the various risk factors associated with osteoporosis in SLE, disease duration, the use of corticosteroids and chronic disease-related damage are consistently reported, with differences between studies probably due to the different populations studied. The role of chronic inflammation in osteoporosis is also important. On the other hand, little attention has been paid to osteoporotic fractures, especially of the vertebra, which are associated with reduced quality of life, increased mortality rates and increased risk of new vertebral and non-vertebral fractures in the general population.
AB - In recent years the survival of patients with systemic lupus erythematosus has increased markedly. Consequently, longterm complications, such as osteoporosis, are currently of paramount importance. SLE is known to increase the risk of bone fractures, and numerous studies have found that SLE patients have osteoporosis. Of the various risk factors associated with osteoporosis in SLE, disease duration, the use of corticosteroids and chronic disease-related damage are consistently reported, with differences between studies probably due to the different populations studied. The role of chronic inflammation in osteoporosis is also important. On the other hand, little attention has been paid to osteoporotic fractures, especially of the vertebra, which are associated with reduced quality of life, increased mortality rates and increased risk of new vertebral and non-vertebral fractures in the general population.
KW - Bone mineral density
KW - Osteoporosis
KW - Systemic lupus erythematosus
KW - Vertebral fractures
UR - http://www.scopus.com/inward/record.url?scp=70350604246&partnerID=8YFLogxK
M3 - Artículo de revisión
C2 - 19891237
AN - SCOPUS:70350604246
SN - 1565-1088
VL - 11
SP - 486
EP - 491
JO - Israel Medical Association Journal
JF - Israel Medical Association Journal
IS - 8
ER -