TY - CHAP
T1 - The use of saporin conjugates to dissect neurons responsible for sleep and wakefulness
AU - Blanco-Centurion, Carlos
AU - Gerashchenko, Dmitry
AU - Murillo-Rodriguez, Eric
AU - Desarnaud, Frank
AU - Shiromani, Priyattam J.
PY - 2005/12/1
Y1 - 2005/12/1
N2 - Virtually all organisms manifest regular periods of behavioral quiescence and activity. In mammals and birds, these periods have evolved into regular episodes of wakefulness and sleep. The sleep period itself has further differentiated into two distinct states, slow wave sleep (SWS) and rapid eye movement (REM) sleep. In humans, SWS has further differentiated into four distinct stages, each identified by a specific pattern on the electroencephalogram (EEG). REM sleep is very similar to wakefulness in many ways; the main difference is that there is behavioral quiescence during REM sleep. For this reason, REM sleep is often referred to as paradoxical sleep.
AB - Virtually all organisms manifest regular periods of behavioral quiescence and activity. In mammals and birds, these periods have evolved into regular episodes of wakefulness and sleep. The sleep period itself has further differentiated into two distinct states, slow wave sleep (SWS) and rapid eye movement (REM) sleep. In humans, SWS has further differentiated into four distinct stages, each identified by a specific pattern on the electroencephalogram (EEG). REM sleep is very similar to wakefulness in many ways; the main difference is that there is behavioral quiescence during REM sleep. For this reason, REM sleep is often referred to as paradoxical sleep.
UR - http://www.scopus.com/inward/record.url?scp=84890203609&partnerID=8YFLogxK
U2 - 10.1007/978-1-59259-896-0_11
DO - 10.1007/978-1-59259-896-0_11
M3 - Capítulo
AN - SCOPUS:84890203609
SN - 9781588291998
SP - 249
EP - 264
BT - Molecular Neurosurgery With Targeted Toxins
PB - Humana Press
ER -